潘文婷

讲师

wentingpan@bjut.edu.cn

基本信息

从事人类疾病及肿瘤相关的分子生物医学领域科研工作，涉及包括动物学、微生物学、分子生物学、基因组学、表观遗传学的科学探究。曾获得国家博士后面上项目、北京市博士后科研基金、朝阳区博士后科研基金及北京工业大学种子基金资助。以第一作者身份或共同第一作者身份在Clinical Cancer Research（CCR），Small，Journal of Biological Chemistry（JBC），Human Molecular Genetics（HMG）等杂志发表研究论文共10余篇；以共同作者参与课题在Nature Medicine，Nature Genetics，Nature Communication，Nanoscale，American Journal of Human Genetics 等杂志发表研究论文30余篇，书籍论著1项等。

研究方向

疾病细胞微环境，肿瘤分子生物学

主要科研项目/课题

[1]2025年新进教师资助计划，10万；

[2]中国博士后第74批面上资助，肝细胞中Mettl3缺失通过招募Spp1巨噬细胞促进肝纤维化进展机制研究，8万;

[3]2023年北京市博士后科研活动经费资助（A创新研发类），CREB1激活通路促进去势前列腺癌阿比特龙治疗耐药机制研究，5万;

[4]血液与健康全国重点实验室开放课题，Mettl3基因对肝脏损伤微环境中巨噬细胞激活的机制研究，2024-2025，10万；

[5]其他合作课题科研项目课题2项；

代表性成果

(1)Wenting Pan; Zhouwei Zhang; Hannah Kimball; Fangfang Qu; Kyler Berlind; Konrad H.Stopsack; Gwo-Shu Mary Lee; Toni K. Choueiri*; Philip W. Kantoff*; Abiraterone Acetate InducesCREB1 Phosphorylation and Enhances the Function of the CBP-p300 Complex, Leading to Resistance in

Prostate Cancer Cells, Clinical Cancer Research, 2021, 2021(27): 2087-2099

(2)Guangyu Zhang#; Xin Zhang#;Wenting Pan#; Xizhao Chen; Lingfei Wan; Chunjie Liu; YutingYong; Yue Zhao; Shuli Sang; Lihua Zhang; Sheng Yao; Yushu Guo; Mingmei Wang; Xinhui Wang;Guangdun Peng; Xinlong Yan; Yanchun Wang; Min Zhang ; Dissecting the Spatial and Single-CellTranscriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in GastricCancer, Advanced science, 2025

(3)Hai-Qing Song#;Wenting Pan#; Rui-Quan Li; Bingran Yu; Wenjuan Liu; Ming Yang*; Fu-Jian Xu*;Rodlike Supramolecular Nanoassemblies of Degradable Poly(Aspartic Acid) Derivatives and HydroxylRich Polycations for Effective Delivery of Versatile Tumor-Suppressive ncRNAs, Small, 2018,14(1703152): 1-13

(4)Wenting Pan#; Nasha zhang#; Wenjuan Liu; Jibing Liu; Liqing Zhou; Yang Liu; Ming Yang ;The long noncoding RNA GAS8-AS1 suppresses hepatocarcinogenesis by epigenetically activating thetumor suppressor GAS8, Journal of Biological Chemistry, 2018, 293(44): 17154-17165

(5)Pomerantz MM, Qiu X, Zhu Y, Takeda DY,Pan W, Baca SC, Gusev A, Korthauer KD, Severson TM, Ha G, Viswanathan SR, Seo JH, Nguyen HM, Zhang B, Pasaniuc B, Giambartolomei C, Alaiwi SA, Bell CA, O'Connor EP, Chabot MS, Stillman DR, Lis R, Font-Tello A, Li L, Cejas P, Bergman AM, Sanders J, van der Poel HG, Gayther SA, Lawrenson K, Fonseca MAS, Reddy J, Corona RI, Martovetsky G, Egan B, Choueiri T, Ellis L, Garraway IP, Lee GM, Corey E, Long HW, Zwart W, Freedman ML. Prostate cancer reactivates developmental epigenomic programs during metastatic progression. Nat Genet. 2020 Aug;52(8):790-799.

招生方向/要求

生物学，生物医学工程